Officials say 14-year-old Alyssa Hussain was last seen in the area of Huron and Sandford streets. They did not specify when this was.
Police describe the teen as female, around five-foot-two, 125 pounds, with black shoulder-length hair and brown eyes.
She was last seen wearing black sweatpants, a black T-shirt and white shoes.
Anyone with information is asked to call the London Police Service at (519) 661-5670 or Crime Stoppers at 1-800-222-TIPS (8477).
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